Cancer and Cardiology
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Understanding Cancer At The Subcellular Level

Author: Jagannath B. Lamture, Ph.D. (Retired, Pune, India)

Series: Cancer Etiology, Diagnosis and Treatments

Publication Date: 2017 - 1st Quarter

Book Description:
The human life is considered most vital of all the living creatures on Earth because humans are bestowed with the highest level of cognition. One can enjoy life if the natural gift, the body, is in a good or healthy condition. A disease is an abnormal condition of the body resulting from infections, toxicity, unfavourable environmental conditions, or illness due to inherited genetic defects in the body. In the past, contagious diseases like the plague resulted in widespread death. About 100 years ago tuberculosis (TB), which is caused by a single bacteria, was one of the deadliest diseases. However, today even a fourth stage TB patient can live a normal life after receiving the allopathic treatment.

Unfortunately, that is not the case with cancer. Today cancer is the most dreaded disease and the #1 killer worldwide. Unlike TB, cancer is difficult to treat as there are more than 100 different types of cancers. However, with a communal (research scientists, both in government and private organizations, government and private funding agencies) undying zeal and drive for finding a cure for cancer, a lot of progress has been made recently in treating different types of cancers, some of them resulting in total cure. Understanding Cancer At The Subcellular Level, delves into the root cause of cancer, which is the mutations in DNA molecules or genes. Further, it elaborates on the risk factors which cause mutations in genes. The internal causes are either inherited faulty genes from one of the parents or changes in genes due to the cell’s internal microenvironments. The external risk factors are many, such as age, alcohol, food, tobacco, etc.

If your health is in a good condition, that means your genes are quite healthy. If DNA or genes are mutated, it leads to the development of diseases including cancer. Multiple mutations in a single gene and multiple mutated genes are needed to develop cancer. Today, with advancements in science and technology, it is possible to offer various treatment options to cancer patients.
The book gives details about: i) signs and symptoms of cancer; ii) causes or risk factors of developing mutations in a healthy gene using the concept of molecular biology at the genetic level; iii) different types of genes and cancers; iv) country specific treatment options; v) estimated treatment costs and vi) dealing with cancer etc. The last chapter is dedicated to definitions of different terms used in this book.

This book covers extremely vital information useful for scientists in research laboratories (such as chemistry, biochemistry, molecular biology, oncology, human genome, bioengineering/genetic-engineering etc.), general physicians, oncologists, all other medical practitioners, students and professors, cancer patients and their relatives and for anyone interested in learning about this abnormality.

Binding: Hardcover
Binding: e-Book

ISBN: 978-1-63485-700-0
ISBN: 978-1-63485-856-4

Price: $230.00
Price: $230.00


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Pathobiology of Hepatocellular Carcinoma and Clinical Impact

Authors: Antonio Mazzocca, Pasquale Agosti and Carlo Sabbà (Interdisciplinary Department of Medicine, University of Bari School of Medicine, Piazza G. Cesare, Bari, Italy)

Series: Cancer Etiology, Diagnosis and Treatments

Publication Date: 2017 - 1st Quarter

Book Description:
This book offers a comprehensive review on hepatocellular carcinoma (HCC) with a particular focus on the relationship between the pathobiology of disease and the clinical aspects including diagnosis and treatment. HCC is becoming one of the most common causes of cancer related death worldwide and is predicted to be the third leading cause of cancer death by 2030. In recent years, the epidemiology of this tumor has undergone a major change, a revolution considering the increased incidence of HCC on NASH and NAFLD in patients with metabolic risk factors. We are witnessing the emergence of new cancer risk factors and new pre-cancerous conditions, especially in countries with a Western lifestyle. Many exciting discoveries in the field of pathogenesis and mechanisms of carcinogenesis have taken place in recent years, including findings from tumor interactions with the host and the microenvironment.

This book aims to provide researchers, medical students and clinicians with a valuable resource for complete and up-to-date research on the pathogenesis of HCC by providing a link between biology and natural history of the disease with clinical implications, including diagnosis, prognosis and therapy. This book offers an in-depth knowledge of HCC pathobiology as well as hints for developing new experimental research lines aiming to improve the understanding and management of the disease, and to prevent the increase of incidence and mortality expected in 2030.

Binding: Softcover
Binding: e-Book

ISBN: 978-1-53610-002-0
ISBN: 978-1-53610-019-8

Price: $95.00
Price: $95.00


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Reduction of Sporadic Malignancies by Stimulation of Cellular Repair Systems and by Targeting Cellular Energy Metabolism

Authors: Borut Poljsak, Thomas N. Seyfried, Dominic P. D’Agostino, Angela M. Poff, and Irina Milisav (University of Ljubljana, Ljubljana, Slovenia)

Series: Cancer Etiology, Diagnosis and Treatments

Publication Date: 2017 - 1st Quarter

Book Description:
About 40% of the population in the industrialized world will develop cancer at some point in their lives,and about half of these people will be cured. Unfortunately, however, approximately one in four Americans alone will die from cancer (over 560,000 Americans each year). Tomasetti and Vogelstein have recently reported that nearly two-thirds of all cancers are caused by random mutations of the body's stem cells. The more random mutations accumulate, the higher the risk of unchecked cell growth, which is a hallmark of cancer development. Knowing the causes of the tumor formation should allow for the development of preventative measures. But what if a tumor is formed due to random mutations during the individual’s lifetime? Are there any preventive methods aside from early detection? Reducing the amount of replicative errors must decrease the accumulation rate of random mutations. In this book, the authors provide an overview of approaches that could influence the formation of cancers caused by random mutations, with a focus on methods aimed at modulating genomic stability and/or strengthening the damage repair processes. Targeting cell metabolism through exposure to moderate stress induced by caloric restriction, physical activity or mimetic compounds can activate endogenous defense mechanisms and cellular repair processes.

Binding: Softcover
Binding: e-Book

ISBN: 978-1-53610-773-9
ISBN: 978-1-53610-837-8

Price: $82.00
Price: $82.00


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Acute Coronary Syndrome (ACS): Diagnosis, Management and Research Insights

Editor: Joan Diaz

Series: Cardiology Research and Clinical Developments

Publication Date: 2017

Book Description:
Acute coronary syndrome (ACS) encompasses a spectrum of clinical entities, ranging from unstable angina (UA), non-ST-segment elevation myocardial infarction (NSTEMI) to ST-elevation myocardial infarction (STEMI). This book analyzes new research on the diagnosis and management of ACS. The first chapter reviews ethnic and gender differences in the diagnosis, risk factors and management of a multiethnic population in Malaysia. Chapter Two summarizes data from available studies conducted over the past last 30 years about pharmacologic reperfusion therapy including comparison with primary angioplasty. Chapter Three discusses the up-to-date available studies that have investigated consent in cardiology.

Binding: Softcover
Binding: e-Book

ISBN: 978-1-53610-803-3
ISBN: 978-1-53610-809-5

Price: $82.00
Price: $82.00


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Horizons in World Cardiovascular Research. Volume 14

Editor: Eleanor H. Bennington

Series: Horizons in World Cardiovascular Research

Publication Date: 2017

Book Description:
In the first chapter of Horizons in World Cardiovascular Research. Volume 14, the secondary mechanical complications of acute coronary syndrome are discussed while presenting initial treatment methods by way of pharmacology. These complications typically occur swiftly (acute phase and subacute phase) and they originate in the severe cardiac expansion zones, in border regions with the healthy tissue as well as the infarcted tissue. The second chapter explains that preeclampsia, a pregnancy-specific syndrome of reduced organ perfusion secondary to vasospasm and endothelial activation, is a major complication in pregnancy, occurring in 7-10% of all pregnant women, and is one of the major causes of maternal morbidity and mortality, preterm birth, intrauterine growth restriction (IUGR), and perinatal mortality. The author explores the way in which markers of endothelial dysfunction could be used to predict hypertensive disorders in pregnancy. The third chapter examines modern percutaneous technologies for the controlling of valvular heart disease, with the goal of pinpointing new opportunities for research. Additionally, the utility of various emerging balloon valvuloplasty techniques, MitraClip, and valve-in-valve approaches are explained in the hopes that understanding their limitations might aid in new research. Molecular domains in heart muscles in family members are classified in the fourth chapter, with the intention of ascertaining the effect of vasodilator agents, sugar, and hypoxia on the operation of protein domains. The domains inside the heart aorta and vein of a slaughtered domestic pig are studied to ascertain how acetylsalicylic acid (ASA), ramipril, sugar, heat and physical exertions influenced them. Next, research on the link between family history of depression and atherosclerotic coronary artery disease is presented in the fifth chapter. Depression is one of the leading contributors to the global burden of diseases, and is one of the major risk factors for cardiovascular disease, therefore it is essential to develop a link between how genetics and inheritance in families may worsen the prognosis of cardiovascular disease in offspring. The sixth chapter supports the claim that ivabradine should be the primary pharmacologic treatment for patients with symptoms of inappropriate sinus tachycardia by ruling out other possible causes.

Binding: Hardcover
Binding: e-Book

ISBN: 978-1-53612-835-2
ISBN: 978-1-53612-836-9

Price: $250.00
Price: $250.00


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Hypertrophic Cardiomyopathy: Causes, Treatment and Research

Editor: Ikram Kammoun (Department of Cardiology, Ariana Hospital, University ElManar, Tunis, Tunisia)

Series: Cardiology Research and Clinical Developments

Publication Date: 2017

Book Description:
Hypertrophic cardiomyopathy (HCM) is the most common form of genetically inherited cardiovascular disease, with a prevalence of one in 500 individuals.
Hypertrophic cardiomyopathy is characterized by both increased ventricular wall thickness in the absence of other causative conditions and potentially fatal arrhythmias.
Tunisian authors, together with recognized specialists in this field from Italy, France, and Austria, offer a broad and detailed discussion of diagnosis, risk stratification and management of HCM.
This book describes recent advances in genetics which provide screening options for affected families, making it essential for modern cardiologists to understand the diagnostic, therapeutic, and prognostic implications of HCM genetic testing.
The diagnostic and prognostic role of cardiac imaging in HCM, with reference to echocardiography and cardiac magnetic resonance, is detailed within this book as well.
The greatest challenge in the management of HCM is identifying individuals who are at an increased risk of sudden cardiac death. This book offers an overview of the most recent data available concerning this stratification.
The obstructive form of HCM is also dealt with in this book with a description of the different catheter-based techniques for septal reduction.
Finally, the topic of management of pregnant women with HCM is addressed.

Binding: Softcover
Binding: e-Book

ISBN: 978-1-53613-003-4
ISBN: 978-1-53613-004-1

Price: $95.00
Price: $95.00


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Horizons in Cancer Research. Volume 64

Editor: Hiroto S. Watanabe

Series: Horizons in Cancer Research

Publication Date: 2017 - 1st Quarter

Book Description:
This book presents original results on the leading edge of cancer research. Chapter One presents an overview of the opportunities and challenges that influence the participation of personalized approach of giving the right drug at the right dose to the right patient. Chapter Two examines malignant mesothelioma. Chapter Three reviews the role of heat-shock proteins and chaperonins in the pathogenesis and progression of cancer. Chapter Four discusses the biosynthesis of LeX family glycosphingolipids and its gene regulation. Chapter Five summarizes how chromosome segregation is accurately controlled and how spindle assembly checkpoint (SAC) monitors this process to maintain segregation fidelity. Chapter Six reviews significant novel findings and the early clinical development of a CD26-targeted therapy for malignant pleural mesothelioma (MPM), and advances that can lead to a more hopeful future for MPM patients. Chapter Seven reviews the pathophysiology and novel treatment strategies in management of peripheral T-Cell lymphoma. Chapter Eight discusses the confirmation behind a role for metformin in cancer therapy and its prospective molecular mechanisms of action. Chapter Nine highlights the role Ganoderma lucidum and its constituents in cancer signaling. Chapter Ten studies the footprint of Ganoderma lucidum in receptor tyrosine kinases.

Binding: Hardcover
Binding: e-Book

ISBN: 978-1-53610-512-4
ISBN: 978-1-53610-534-6

Price: $250.00
Price: $250.00


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Chemoradiotherapy: Concurrent Uses, Efficacy and Impact on Prognosis

Editor: Daniel Sullivan

Series: Cancer Etiology, Diagnosis and Treatments

Publication Date: 2017 - 1st Quarter

Book Description:
Chemoradiotherapy is the use of both chemotherapy and radiotherapy for the treatment of cancer. This book discusses it's concurrent uses, efficacy in the medical field, and the impact it has on the prognosis of cancers.

Binding: Softcover
Binding: e-Book

ISBN: 978-1-53610-704-3
ISBN: 978-1-53610-722-7

Price: $82.00
Price: $82.00


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Horizons in Cancer Research. Volume 65

Editor: Hiroto S. Watanabe

Series: Horizons in Cancer Research

Publication Date: 2017 - 1st Quarter

Book Description:
This book presents original results on the leading edge of cancer research. Chapter One provides a comprehensive discussion to address the potential benefits of myricetin on cancer, diabetes, and neurodegenerative disease. It also discusses the underlined mechanism involved in the biological action of myricetin. Chapter Two discusses the clinical significance of vasculogenic mimicry. Chapter Three studies bacterial toxins as a direct cause of cancer. Chapter Four examines the immunological aspect of stroma in ovarian cancer. Chapter Five focuses on immune checkpoint inhibitors in the treatment of solid tumors. Chapter Six provides a review of targeting non-coding mitochondrial RNAs in gynecological and urinary malignancies. Chapter Seven explores the NF-κB signaling pathway, and its targeting in human cancer treatment. Chapter Eight analyzes the circadian rhythm and skin cancer prevention. The final section of this book is a short commentary on melanoma.

Binding: Hardcover
Binding: e-Book

ISBN: 978-1-53610-944-3
ISBN: 978-1-53610-954-2

Price: $250.00
Price: $250.00


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Horizons in Cancer Research. Volume 66

Editor: Hiroto S. Watanabe

Series: Horizons in Cancer Research

Publication Date: 2017 - 1st Quarter

Book Description:
This book presents original results on the leading edge of cancer research. Chapter One provides a brief overview of the recent updates in the role of the laboratory in establishing the diagnosis, methods of disease monitoring and mechanisms that contribute to tyrosine kinase inhibitor (TKI) resistance for patients with chronic myeloid leukemia. Chapter Two reviews self-esteem and academic difficulties in preadolescents and adolescents health from pediatric leukemia. Chapter Three analyzes the role of lactoferrin expression in the initiation and progression of most common hormone-dependent cancers. Chapter Four studies the ETS transcription factor FLI-1 as an important player in human cancer. Chapter Five highlights the latest advances in DNA methylation signature- based liquid biopsy. Chapter Six presents data concerning the pharmacological activity of water-soluble complex of quercetin with polyvinylpyrrolidone on the process of bleomycin-induced lung fibrosis in mice. Chapter Seven investigates prospects of enhancing anti-cancer activities of quercetin in the treatment of glioblastoma. Chapter Eight discusses the correction of tumor-associated thrombocytopenia by quercetin. Chapter Nine examines robotic surgery for prostate cance

Binding: Hardcover
Binding: e-Book

ISBN: 978-1-53611-011-1
ISBN: 978-1-53611-018-0

Price: $250.00
Price: $250.00


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Horizons in Cancer Research. Volume 67

Editor: Hiroto S. Watanabe

Series: Horizons in Cancer Research

Publication Date: 2017 - 2nd Quarter

Book Description:
This book presents original results on the leading edge of cancer research. Chapter One reviews microRNAs as a novel diagnostic and predictive biomarker in human cancer. Chapter Two discusses the deregulated expression and function of S100 proteins in cancer cells. Chapter Three studies the current management of nasopharyngeal carcinoma and future directions in clinical research. Chapter Four examines the human papillomavirus vaccine.

Binding: Hardcover
Binding: e-Book

ISBN: 978-1-53611-038-8
ISBN: 978-1-53611-058-6

Price: $250.00
Price: $250.00


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Horizons in Cancer Research. Volume 68

Editor: Hiroto S. Watanabe

Series: Horizons in Cancer Research

Publication Date: 2017 -3rd Quarter

Book Description:
High-grade gliomas are the most frequent primitive brain malignancies of the adult and account for approximately 60-75% of all gliomas. Chapter One concludes the progress in the management of high-grade gliomas requires the simultaneous and synergic effort of a multitude of health professionals including neurosurgeons, neuroncologists, neurointerventionalists, radiologists, immunologists and neuropathologists among others. Chapter Two describes the fundamental molecular mechanisms involved in the understanding of metastatic growth, the role of some metastasis suppressor proteins in the regulation of these processes in different types of cancer, and the clinical implications of these metastasis suppressors. Chapter Three highlights the reported knowledge regarding the secretion, regulation and therapeutic potential of melatonin in the prevention of cancer. Chapter Four reviews the current status of different oncolytic viruses and the molecular mechanism of viral oncolysis in the context of thoracic malignancies. Chapter Five suggests Coordination Dynamics Therapy can inhibit the growth of different kinds of cancer, especially breast cancer. Chapter six argues that the long term health outcomes of bilateral surgical oophorectomy justify that in the majority of cases, the defect of hormonal and metabolic equilibrium leads to decreased cellular estrogen surveillance and an increase in both morbidity and mortality. Chapter seven evaluates the importance of assessing HPV status as a clinically relevant biomarker and to study the therapeutic implications for the appropriate management of HPV-related OPSCC. Chapter eight covers the complex and multiform network of actions by MicroRNA, and the value of miRNAs in oncology as diagnostic and prognostic indicators.

Binding: Hardcover
Binding: e-Book

ISBN: 978-1-53612-249-7
ISBN: 978-1-53612-258-9

Price: $250.00
Price: $250.00


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Triple-Negative Breast Cancer: Biomarkers, Emerging Therapeutic Strategies and Clinical Challenges

Editor: Marion Montgomery

Series: Cancer Etiology, Diagnosis and Treatments

Publication Date: 2017-3rd Quarter

Book Description:
Poorly differentiated triple negative breast cancers (TNBCs) were first characterized in the literature in 2005 by the absence of receptors for estrogen (ER) and progesterone (PR) as well as the lack of tyrosine kinase human epidermal growth factor receptor 2 (HER-2). Clinically, TNBCs exhibit fairly aggressive local growth, rapid progression and account for a high rate of early metastases, most commonly to visceral organs and central nervous system. Chapter One describes how the last decade has contributed to our understanding of the function of exosomes in the progression of breast cancer. Furthermore, it will discuss the implications for using exosomes from body fluids as biomarkers in diagnosis and treatment strategies. Chapter Two discusses how the strong correlation between BRCA gene mutations and the high risk of TNBC proposes certain mediators between germline mutations and the risk for poorly differentiated breast cancers. Chapter Three presents increasing evidence of the role of tumor lymphocytic immune infiltrates in this subtype of breast cancer. High levels of tumor infiltrating lymphocytes (TILs), mainly in lymphocyte-predominant breast cancer (LPBC), have been associated with improved disease-free and overall survival rates in TNBC patients with and without any treatment.

Binding: Softcover
Binding: e-Book

ISBN: 978-1-53612-372-2
ISBN: 978-1-53612-390-6

Price: $82.00
Price: $82.00


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Constrictive Pericarditis and Cardiac Tamponade: Epidemiology, Causes and Management

Editors: Jonathan N. Bella and Andrew Yoon (Division of Cardiology, Bronx-Lebanon Hospital Center and Icahn School of Medicine at Mount Sinai, NY, USA)

Series: Cardiology Research and Clinical Developments

Publication Date: 2017

Book Description:
The major impetus for the design and execution of Constrictive Pericarditis and Cardiac Tamponade: Epidemiology, Causes and Management has been the extraordinary wave of breakthrough discoveries in the diagnosis and management of pericardial diseases over the past few decades. Modern advancements in cardiac imaging, including tissue Doppler imaging, cardiovascular computed tomography (CT), and cardiac magnetic resonance imaging (MRI), have allowed for increased accuracy and earlier detection of both constrictive pericarditis and cardiac tamponade. This book is designed to summarize and critically analyze the current understanding of these disease states for a broad audience of internists and cardiologists.
There are an abundance of books, review articles, and internet sources that do an excellent job of describing the physiology/pathophysiology of the pericardium and the many pericardial diseases. Constrictive Pericarditis and Cardiac Tamponade: Epidemiology, Causes and Management differs from those other sources in that a conscious effort was made to present the information in this textbook in a “how to” format, with the chapters and text structured in such a way as to provide the reader with a clear step-by-step narrative. Clinical signs and symptoms are reviewed in detail first, followed sequentially by echocardiographic, CT, MRI, and invasive hemodynamic findings. High-quality images, figures, and illustrations were also specifically chosen and arranged to accompany the text in order to provide easy visual reference for the reading physician, whenever the diagnosis of pericardial disease is relevant to their patient’s care. As such, this book seeks to provide reassurance to clinically-oriented internists and cardiologists when caring for patients with suspected pericardial disease.

Binding: Hardcover
Binding: e-Book

ISBN: 978-1-53610-663-3
ISBN: 978-1-53610-679-4

Price: $160.00
Price: $160.00


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Thyroid Nodules and Cancer: A Simplified Case Oriented Approach

Editors: Jeffrey Lynn Miller and Edmund deAzevedo Pribitkin (Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA)

Series: Endocrinology Research and Clinical Developments
Cancer Etiology, Diagnosis and Treatments

Publication Date: 2017 - 1st Quarter

Book Description:
This practical guide to the management of thyroid nodules and cancer offers the practitioner a common-sense approach to the management of an increasingly common clinical problem. Thyroid cancer is the most rapidly increasing cancer diagnosis in the United States and is now the fifth most common cancer among women. Indeed, an estimated 65,000 adults (15,000 men and 50,000 women) in the United States will be diagnosed this year with thyroid cancer. Many more will be treated for thyroid nodules.

Unfortunately, practice patterns still vary greatly across the country and the world. Many patients we believe are inappropriately treated. Practitioners seeking to help their patients and make sense of conflicting thyroid cancer guidelines will discover illustrative cases that represent common situations in clinical practice. Unlike encyclopedic guidelines and impenetrable textbooks, this straightforward casebook engages, informs and entertains the reader. Even so, the book’s scenarios cover a broad range of clinical presentations from incidental microcarcinomas to invasive metastatic cancers. Here, molecular diagnostics and advanced imaging are demystified and incorporated into common-sense approaches stressing the importance of personalized care. And readers seeking deeper understanding will be guided in the book’s digital version with hyperlinks to primary source material.

Binding: Softcover
Binding: e-Book

ISBN: 978-1-53610-636-7
ISBN: 978-1-53610-653-4

Price: $82.00
Price: $82.00


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Oncology: The Promising Future of Biomarkers

Editors: Anthony Furfari, George S. Charames, Rachel McDonald, Leigha Rowbottom, Azar Azad, Stephanie Chan, Bo Angela Wan, Ronald Chow, Carlo DeAngelis, Pearl Zaki, Edward Chow, Joav Merrick (Odette Cancer Centre, Sunnybrook Health Sciences Centre, CA)

Series: Health and Human Development (Joav Merrick - Series Editor - Medical Director, Ministry of Social Affairs, Jerusalem, Israel)

Publication Date: 2017 - 1st Quarter

Book Description:
Cancer is a term that describes a constellation of diseases that affect a large proportion of the global population. By 2020, it is estimated there will be 15 million new cancer cases worldwide and a corresponding 12 million cancer-related deaths. There are many efficacious treatments for cancer with both curative and palliative intents, which regardless of efficacy, can result in distressing symptoms including pain, fatigue, nausea, vomiting, and reduced function. Compounded with very similar symptoms from the disease itself, toxicities can ultimately lead to diminished quality of life (QOL). In recent years, the use of biomarkers in cancer research and practice has become a widely discussed topic of exploration for researchers and clinicians alike. A biomarker is a biological property that can be measured and used as a tool in the prevention, diagnosis, and treatment of specific illnesses, including cancer. In this book, the authors synthesize existing biomarker research in the literature related to cancer and the potential effect it may have on future treatment, drug metabolism, symptom burden, radiation response, susceptibility to radiation related toxicities, and prognosis.

Binding: Hardcover
Binding: e-Book

ISBN: 978-1-53610-608-4
ISBN: 978-1-53610-610-7

Price: $195.00
Price: $195.00


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Cancer versus Nutraceuticals

Editors: S. Gowtham Kumar and V. K. Langeswaran (Faculty of Allied Health Sciences, Chettinad Hospital and Research Institute, Chettinad University (A Grade-NAAC), India)

Series: Cancer Etiology, Diagnosis and Treatments

Publication Date: 2017 - 4th Quarter

Book Description:
Chemoprevention is the use of tiny molecules that include nutritional substances or herbal products to avoid cancers. They are different from chemotherapeutics, where synthetic chemicals are used to eliminate or improve cancer progression. Numerous clinical trials have established the efficiency of using raloxifene and tamoxifen (both are estrogen receptor antagonists), and fenretinide, an artificial retinoid that aids in the defense against mammary cancer. Nutraceuticals, which are generally photochemicals obtained from nutritional or medicinal plants sources like garlic, cauliflower, soya bean, ginger, honey and tea may have chemopreventive properties, which have already been reported through numerous research studies. The genesis of a tumor is a frequently deliberate progression, and the threat of developing cancer increases with age. Changing a diet that includes the intake of useful photochemicals could manipulate the balance and accessibility of dietary chemopreventive agents. This imposes further consideration as to how photochemicals could potentially maintain healthy cells. Providentially, there is an excess of plant-based photochemicals even though a small number of of them are well characterized for their use in cancer chemoprevention. Several original approaches to cancer prevention are being studied, some of which are showing a considerable guarantee of saving lives in a cost-effective manner. This reference book consists of eight chapters with different approaches and aspects to cancer prevention. This could be a book of choice for students enrolled in undergraduate & postgraduate medicine, allied health science students as well as for students with futures within India’s healthcare system.

Binding: Hardcover
Binding: e-Book

ISBN: 978-1-53612-529-0
ISBN: 978-1-53612-531-3

Price: $160.00
Price: $160.00


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Palliative Care: Oncology Experience from Hong Kong

Editors: Louisa Cheuk-Yu Lui, Kam-Hung Wong, Rebecca Yeung, Joav Merrick (Medical Director, Health Services, Division for Intellectual and Developmental Disabilities, Ministry of Social Affairs and Social Services, Jerusalem, Israel)

Series: Health and Human Development (Joav Merrick - Series Editor - Medical Director, Ministry of Social Affairs, Jerusalem, Israel)

Publication Date: 2017 - 4th Quarter

Book Description:
Training in palliative medicine for clinical oncologists in Hong Kong is organized by the Palliative Medicine Subspecialty Board under the Hong Kong College of Radiologists, and it is expected that through this training the oncologists will be equipped to provide good quality palliative care for their cancer patients. As part of the training and subspecialty certification, the candidates must submit a research project of high scientific standard. In this book, the authors present some of the research conducted during the last examination and certification. The research covered different topics including radiotherapy in patients with metastatic diseases, survival predictors, a systemic review on drugs, and advanced directives in the Chinese population. The authors hope that this presentation will provide insight to the progress of palliative care development in different facilities in Hong Kong

Binding: Softcover
Binding: e-Book

ISBN: 978-1-53612-397-5
ISBN: 978-1-53612-430-9

Price: $82.00
Price: $82.00


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Cancer and Exercise

Editors: Leila Malek, Fiona Lim, Bo Angela Wan, Patrick L Diaz, Ph.D., Edward Chow, Joav Merrick, M.D. (Medical Director, Health Services, Division for Intellectual and Developmental Disabilities, Ministry of Social Affairs and Social Services, Jerusalem, Israel)

Series: Health and Human Development (Joav Merrick - Series Editor - Medical Director, Ministry of Social Affairs, Jerusalem, Israel)

Publication Date: 2017 - 4th quarter

Book Description:
With advances in knowledge and technology, the proportion of cancer patients who have been cured or survive with cancers is growing, but a certain proportion of patients will still have disease recurrence or progression to palliative care. During the entirety of cancer progression, significant adverse impacts on physical and psychological aspects have been observed due to both diseases themselves and the associated treatments. “Exercise-oncology” is an emerging field of research that has gained increasing attention since the term was first publicly introduced during the 1980s, showing improved functional capacity, body composition and treatment-related nausea with aerobic exercise. In this book, the authors review the current evidence on the application of exercise in various time points during cancer care, including as a preventive measure before cancer development, as a treatment during cancer treatments, as a rehabilitation measure during the recovery phase, and as a supportive measure during palliative care. Proposed mechanisms and published data from various studies will be evaluated, and finally guidelines on exercise prescription during cancer care will also be discussed.

Binding: Hardcover
Binding: e-Book

ISBN: 978-1-53612-747-8
ISBN: 978-1-53612-748-5

Price: $160.00
Price: $160.00