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Zoonomia. Volume I: The Laws of Organic Life

Author: Erasmus Darwin, M.D.

Series: Animal Science, Issues and Research

Publication Date: 2019

Book Description:
This 2 volume set is written by the grandfather of Charles Darwin. The purpose of the books is to reduce the facts belonging to animal life into classes, orders, genera, and species; and, by comparing them with each other, to unravel the theory of diseases.

Binding: Hardcover
Binding: e-Book

ISBN: 978-1-53614-872-5
ISBN: 978-1-53614-873-2

Price: $250.00
Price: $250.00


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Introduction to the Three-Plane Corpuscular-Wave Biology of Forest Tree Species

Author: Nina F. Kuznetsova
(All-Russian Research Institute of Forest Genetics, Breeding and Biotechnology
Federal Forestry Agency, Ministry of Natural Resources and Ecology of the Russian Federation)

Series: Plant Science Research and Practices

Publication Date: 2019

Book Description:
This book is based on one unifying concept – the concept of a three-plane corpuscular-wave organization of biological systems, using the example of the prokaryotic and eukaryotic cells, and a life cycle of forestry tree plants. The range of questions and problems is not only numerous, but also controversial. Particular attention is paid to the description of plant biology on the basis of the general principles and fundamental laws of physics; the trinity principle of DNA energy, DNA particles and DNA information at different levels of their organization; the fundamental unity of living and non-living matter, etc. Presently, these directions of biophysics are still at the stage of formation. Some theoretical basics of the concept have already been described in the authors’ previous work, Corpuscular-Wave Nature and Wave Properties of Plant Cells, published by Nova Science Publishers, 2013. These concepts include the corpuscular-wave nature of DNA; the notion about a cell as a quantum-mechanical system, an open and closed system, or an equilibrium system; the nature of two internal sources of energy; etc. Many theoretical statements have yet to be formulated by future researchers, and the authors mean to set the stage by setting up the next objectives. Firstly, they hope to show how many biological processes and mechanisms possess wave nature, with special analysis concerning the unique biotechnologies that were created by nature in plants. The possibility of such an analysis is provided by wide ranging experimental material, which has accumulated by studying cell biology, molecular biology, biophysics, development biology, forest and classical genetics, etc. Secondly, and more importantly, the authors wish to promote the expansion of research in this field. Particular attention in this book is given to the ecological issues that include the peculiarities of the formation of genotype-environmental connections at different stages of the life cycle; intra-specific selection; the mechanisms and adaptive devices ensuring the contact of genetic material with the environment and the relative independence from it; the preservation of genotypic diversity; cross- and self-pollination; and other processes, which provide the viability, quality and sustainability of forest ecosystems in a constantly fluctuating environment.
The material presented in the book embraces the different areas of biology and physics (classical and quantum). It consists of two different parts. A three-plane corpuscular-wave model concerning the organization of prokaryotic and eukaryotic cells is presented in the theoretical Part One. The questions connected with the initiation of the reproductive process and the inception of generative organs, the formation of the energetic, corpuscular and informational programs, and the creation of a three-plane matrix of corpuscular-wave organization are analyzed in Part Two (Chapters One through Three). These processes of sexual reproduction are species-specific, and so they are described often in the example of only one species (Pinus sylvestris L.). Different aspects of development for a forest tree species, formation of the population gene pool, and the physical models of different functional systems of forest tree species are discussed in Chapters Four and Five.

Binding: Hardcover
Binding: e-Book

ISBN: 978-1-53614-411-6
ISBN: 978-1-53614-412-3

Price: $230.00
Price: $230.00


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Zoonomia. Volume II: The Laws of Organic Life

Author: Erasmus Darwin, M.D.

Series: Animal Science, Issues and Research

Publication Date: 2019

Book Description:
This 2 volume set is written by the grandfather of Charles Darwin. The purpose of the books is to reduce the facts belonging to animal life into classes, orders, genera, and species; and, by comparing them with each other, to unravel the theory of diseases.

Binding: Hardcover
Binding: e-Book

ISBN: 978-1-53614-874-9
ISBN: 978-1-53614-875-6

Price: $275.00
Price: $275.00


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The Origin of Species by Means of Natural Selection. 6th Edition.

Author: Charles Darwin

Series: Science, Evolution and Creationism

Publication Date: 2019

Book Description:
The Origin of Species by Means of Natural Selection, published in 1859 sold out on its first day. It is considered to be the foundation of evolutionary biology and is based on Darwin’s experiences while onboard the H. M. S. Beagle. The sixth edition is often considered the definitive work and contains many additions and corrections to the original book.

Binding: Hardcover
Binding: e-Book

ISBN: 978-1-53614-939-5
ISBN: 978-1-53614-940-1

Price: $350.00
Price: $350.00


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Enter the World of Microbiology: Interviews about the World’s Most Famous Microbiologists

Authors: Manuel Varela
Eastern New Mexico University, Portales, New Mexico, USA

Michael F. Shaughnessy
Eastern New Mexico University, Portales, New Mexico, US

Series: Microbiology Research Advances

Publication Date: 2019

Book Description:
Enter the world of microbiology: A dimension not only of viruses and bacteria, but also of contributions to medicine, health, and well-being. Enter the world of the most famous discoveries of scientists in the realm of biology from all over the world. Learn about their lives and the discoveries that have revolutionized science and the field of microbiology. These are the geniuses that have given the human race so much to improve the health of all mankind

Binding: Hardcover
Binding: e-Book

ISBN: 978-1-53615-168-8
ISBN: 978-1-53615-169-5

Price: $195.00
Price: $195.00


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Halophytes: Identification, Characterization and Uses

Editor: Rolando Tucker

Series: Plant Science Research and Practices

Publication Date: 2019

Book Description:
Areas with high agricultural potential include arid zones, which make up 43% of the world’s total area. In these areas the scarce precipitation and the high salinity of the soils represent a limitation for the development of conventional agriculture. For this reason, it is essential to guide the efforts of research to generate agricultural technologies that allow us to optimize the productivity of those areas. Halophytes have a wide diversity of plant forms and have been regarded as a rich source of potential new crops.

Next, the nutritional profile of four promising species of chenopodiaceae family are collected from saline areas of Iran were evaluted by standard methods. The nutrient content of four halophyte plants indicate that they have high nutritive and dietary values, so these medicinal plants can be used as a major source of minerals and natural nutrients in food and fodder, based on their crude protein, fat, fiber, carbohydrate, vitamins and minerals in sufficient amount.
The physiological mechanisms underlying the ability of halophytes to grow well under saline soils are explored. Additionally, several theories of growth stimulation mechanisms advocated in the past and presumed mechanisms of growth stimulation are discussed in the context of the latest reports.

The authors go on to review the potential of halophytes for various uses in the Mediterranean area and assess how a knowledge of their cellular machinery can help to determine the best species and genotypes for their applied uses.
Following this, the ancient and present-day uses of halophytes in Portugal are presented and discussed, focusing on their traditional uses and biological activities. The review concludes by suggesting future requirements and perspectives for further exploitation of these species within the context of sustainability and climate change.

In southern parts of Iran for combating dust storm, people have started growing halophyte plants and trees such as Tamarix with drainage water. C. tubulosa which is collected from the central plateau of Iran has shown a high amount of K, Mg, S, Ca and P and antioxidant capacity as well as six important phenylethanoid glycoside substrates. Cistanche could be recommended to improve the economy of the area and employment, which can also encourage the local people to plant more trees and protect them.

Binding: Hardcover
Binding: e-Book

ISBN: 978-1-53614-707-0
ISBN: 978-1-53614-728-5

Price: $160.00
Price: $160.00


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Lampreys: Evolution, Distribution and Use in Research

Editor: Raymond Moss

Series: Marine and Freshwater Biology

Publication Date: 2019

Book Description:
At present, two native lamprey species occur in the Czech Republic, namely the brook lamprey and the Ukrainian lamprey. Lampreys: Evolution, Distribution and Use in Research begins by summarizing the available knowledge about the biology, ecology, distribution, monitoring of occurrence and action plans/recovery programmes for the aforementioned species.

Following this, the occurrence of lampreys of the genus Lethenteron in 19 rivers and one lake in Sakhalin Island is documented, and sex differences in adults in respect to morphometric parameters are also presented.

Mammalian blood clotting is presented as an extremely complex phenomenon involving more than two dozen proteins interacting in a series of limited proteolytic events partitioned into two calcium-dependent pathways. Some clotting proteins in mammals are present in only trace amounts, and proving their absence or presence in lampreys was not possible until the era of whole genome sequencing. As such, the authors retrace this development from a personal standpoint.

Binding: Softcover
Binding: e-Book

ISBN: 978-1-53614-638-7
ISBN: 978-1-53614-706-3

Price: $82.00
Price: $82.00


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Mosquitos: Species, Distribution and Disease

Editor: Tabitha Terry

Series: Insects and Other Terrestrial Arthropods: Biology, Chemistry and Behavior

Publication Date: 2019

Book Description:
Mosquitos: Species, Distribution and Disease opens with a discussion on the potential use of plant-derived saponins as a natural larvicide to help prevent and control disease outbreaks in mosquito-infested areas. The general background of saponins, examples of saponin-containing plants and the uses of crude saponins are furthermore discussed. The authors develop practical perspectives on controlling tropical disease vectors in an eco-friendly manner.

The authors also provide updated lists of the mosquito species present in the eastern states of the Arabian Peninsula, with information on their collection sites and distribution. New records of some adults are published for the first time from Qatar. An investigation of the morbidity of epidemic vector-borne diseases is also considered.

Intracellular population dynamics of viruses under a set of biologically sound parameter values are studied, and statistical tools are used to quantify the estimability of model parameters under distinct scenarios. The resulting mathematical model can also be applied in clinical settings where there is a growing body of work on the within-host dissemination of flaviviruses.

Binding: Hardcover
Binding: e-Book

ISBN: 978-1-53615-157-2
ISBN: 978-1-53615-158-9

Price: $160.00
Price: $160.00


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Calmodulin: Structure, Mechanisms and Functions

Editor: Vahid Ohme

Series: Cell Biology Research Progress

Publication Date: 2019

Book Description:
In Calmodulin: Structure, Mechanisms and Functions, the authors consider small and poorly-studied groups of plant calcium-dependent protein kinases that directly interact with calmodulin molecules. In plants, Ca2+ activates calmodulin-like domain kinases that do not require calmodulin or phospholipids. Thus these kinases differ from both CaMK and PKC families prevalent in mammalian cells.

Next, various strategies of purification of recombinant proteins using CaM-based purification systems are reviewed and discussed. Protein purification is a crucial process in biotechnology industries and life science research laboratories. Amongst these purification strategies, affinity purification has garnered a lot of attention due to its higher speed and selectivity, leading to enhanced purity in fewer steps.

In the closing chapter, the authors describe atomic-level structures of Ca2+-bound CaM (Ca2+/CaM) bound to the PSD-95 N-terminal domain. The N-lobe of CaM forms a cap that binds to the N-terminus of PSD-95 and sterically blocks the palmitoylation of PSD-95 at Cys3 and Cys5. The CaM C-lobe forms hydrophobic contacts with PSD-95 residue Y12, and the Y12E mutation abolishes Ca2+-induced postsynaptic release of PSD-95.

Binding: Softcover
Binding: e-Book

ISBN: 978-1-53614-948-7
ISBN: 978-1-53614-949-4

Price: $82.00
Price: $82.00


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Acetylcholine Receptors in Health and Disease

Editor: Adelais Eros Gupta

Series: Neuroscience Research Progress

Publication Date: 2019

Book Description:
Acetylcholine Receptors in Health and Disease opens with a review of the results of an investigation on the cholinergic modulation of excitatory synaptic transmission in the frog tectum carried out in the laboratory of neurophysiology at the Lithuanian University of Health Sciences. Experiments were done in vivo on the common grass frog Rana temporaria.

Next, the authors review the function of M4 MR and discuss possible detection methods. M4 MR regulated locomotion is studied in conjunction with recent data on consequences to biorhythms.

In the closing chapter, the authors review the environmental enrichment paradigm in rodents, as well as their effects on neurobiological, physiological and behavioral variables in preclinical studies.

Binding: Softcover
Binding: e-Book

ISBN: 978-1-53615-447-4
ISBN: 978-1-53615-448-1

Price: $82.00
Price: $82.00


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Human Serum Albumin: Structure, Binding and Activity

Editor: Dianne Cohen

Series: Pharmacology – Research, Safety Testing and Regulation

Publication Date: 2019

Book Description:
Human serum albumin is found in the intravascular and extracellular space and is the main protein of human blood plasma which binds water, cations (such as Ca2+, Na+, K+), fatty acids, hormones, bilirubin, thyroxin (T4) and pharmaceuticals. Structurally, the serum albumins are similar, each domain containing five or six internal disulfide bonds. In the opening chapter of Human Serum Albumin: Structure, Binding and Activity the authors review the structure, content and binding of Human Serum Albumin.

Then, the role of albumin in free radical trapping activities and as an oxyradical scavenger is described. A discussion of recent advances in the use of the antioxidant properties of human serum albumin to make drugs detectable in vivo is also presented.

Human serum albumin has one tryptophan residue and shows a characteristic fluorescence of around 350 nm under ultraviolet irradiation. Because tryptophan is easily oxidized by reactive oxygen species and/or photoexcited molecules through electron transfer (leading to fluorescence diminishment) a fluorometry of this tryptophan residue is a useful tool to evaluate oxidation. In light of these characteristics, the authors examine the photosensitizing activity of organic photosensitizers, including porphyrins and phenothiazine dyes.

The use of magnetic resonance imaging and spectroscopy for the determination of human serum albumin structure, drug binding and in vivo activity is explored, in addition to drug modifications using human serum albumin.

Following this, this compilation studies the major approaches for the characterization of human serum albumin as a fluorinated drug delivery agent and fluorinated albumin influence on drug binding. Synthesis and characterization of fluorinated conjugates of albumin and adsorbed human serum albumin on surfaces containing CF3 are also discussed.

The concluding study investigates possible similarities and differences in albumin concentration and the presence of tyrosine in urine from a population of healthy and microalbuminuria dependent women. The assessment of subtle changes in albumin concentration, the primary macromolecular component of urine, is critical for the diagnosis of early stage albuminuria, one of the major complications in nephropathy.

Binding: Softcover
Binding: e-Book

ISBN: 978-1-53614-787-2
ISBN: 978-1-53614-788-9

Price: $82.00
Price: $82.00


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Advances in Medicine and Biology. Volume 136

Editor: Leon V. Berhardt

Series: Advances in Medicine and Biology

Publication Date: 2019

Book Description:
Discovered in 1961, amiodarone is a cationic amphiphilic molecule which belongs to class III antiarrhythmic drugs and therefore, it is used in the treatment of a wide range of cardiac arrhythmias. Advances in Medicine and Biology. Volume 136 begins by discussing state of the art formulations of amiodarone and outlooks for future dosage forms.

Though amiodarone hydrochloride has often been prescribed for patients with refractory or life-threatening arrhythmias, its clinical use is frequently limited because of a number of side effects such as corneal microdeposits, photosensitivity, pulmonary fibrosis, thyroid and liver dysfunction, and peripheral neuropathy. As such, the authors conduct a study wherein amiodarone hydrochloride dose-dependently induced cell death, lysosomal storage of phospholipids and neutral lipids, and oxidative stress in immortalized Schwann cells.

The following review presents scientific results and popular uses for plants from the Euphorbia genus. With nearly 2,000 species, Euphorbia is the third largest genus of blossoming plants, promptly discernable by their milky latex and particular inflorescences, called cyathia.

The laryngeal mask airway was introduced by Dr. Archie Brain in 1981 with the intent to develop a safe and effective alternative to orotracheal intubation. Since its first use in the early 90s, the laryngeal mask airway went through many structural changes and has greatly evolved. This compilation addresses this evolution and suggests that the laryngeal mask airway is a safe and easy to use device that can be considered an effective alternative to more invasive tools.

Also studied in this collection is the recent development and modern trends in the use of mesenchymal stem cells for the regeneration of damaged myocardium. Cardiovascular diseases are the main cause of death worldwide and there is no promising treatment available for cardiomyopathies except some pharmacological and surgical interventions including heart transplantation.

Obesity is associated with the chronic inflammatory condition, and a consequence of obesity is the development of cardiovascular diseases due to the presence of risk factors such as hypertension and dyslipidemia. The authors present a study is presented which analyzes recent literature data related to the link between obesity and development of cardiovascular diseases.

Following this, the authors discuss echinococcosis, a zoonotic infectious disease caused by the larval stages of four species of genus Echinococcosis, including, Echinococcus granulosus, E. multilocularis, E. oligarthrus and E. vogeli. Imaging methods for detecting space occupying lesions are the primary approaches for diagnosing of human Echinococcosis.

The clinical presentation, diagnosis and management of classical Kaposi’s sarcoma is also discussed. Classical Kaposi’s sarcoma predominantly develops in immunocompetent older males of Mediterranean or Jewish origin and is considered the most indolent of the four variants of the disease. Human herpes virus 8 is believed to be the etiological factor.

In the penultimate chapter, the authors suggest presenting experimental data in the form of hybridization energy isotherms. Theory has demonstrated a relationship between the free energy of oligo-target duplex interaction and the hybridization signal. Moreover, it has been found that target concentration changes are causing vertical shifts of hybridization energy isotherms.

Lastly, a short introduction to microphysiometry (the monitoring of energy metabolism of living cells) is given. An experiment with the mouse fibroblast cell line L929 is described, employing the intelligent mobile lab for in vitro diagnostics. The experimental conditions are described with a focus on the medium exchange and rest intervals which result in a metabolism frequency of the living cells.

Binding: Hardcover
Binding: e-Book

ISBN: 978-1-53614-722-3
ISBN: 978-1-53614-723-0

Price: $250.00
Price: $250.00


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Advances in Medicine and Biology. Volume 137

Editor: Leon V. Berhardt

Series: Advances in Medicine and Biology

Publication Date: 2019

Book Description:
Advances in Medicine and Biology. Volume 137 begins by presenting a systematic view on the electromagnetic properties of blood and its components. Detailed data on electric impedance, conductivity and dielectric permittivity of native blood in healthy persons and patients with different diseases before and after treatment are also presented.

The authors go on to discuss the concept of hydrogels, microgels and nanogels; smart/intelligent colloidal gels; classification of nanogels; synthesis of nanogels; and applications in patient compliant drug delivery.

Following this, two components involved in triacylglycerol breakdown are discussed: lipolysis and antilipolysis. Fat cells exhibit insulin receptors mediating the well-known antilipolytic properties of the pancreatic hormone. However, various receptors negatively coupled to the adenylyl-cyclase also limit lipolytic activity.

The development of oral vaccines by two molecular display systems (using Saccharomyces cerevisiae and Lactobacillus casei as hosts) is explored, as well as the oral administration of enolase using a mouse model.

A study is included on zebrafish, which have been used disease models for pathogenesis and drug screening due to the availability of in vivo genetic and molecular tools. Issues from the perspective of morpholino usage in the field of aquatic toxicology are also debated.
The closing chapter examines “moonlighting” metabolic enzymes, such as enolases, and the role they play in transporting tRNAs and presenting cell surface antigens within and outside of cells.

Binding: Hardcover
Binding: e-Book

ISBN: 978-1-53614-805-3
ISBN: 978-1-53614-806-0

Price: $250.00
Price: $250.00


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Protein Hydrolysates: Uses, Properties and Health Effects

Editor: Sheri Sims

Series: Biochemistry Research Trends

Publication Date: 2019

Book Description:
In this collection, the authors aim to provide information the preparation of marine protein hydrolysates and their main bioactive properties such as antioxidant, antimicrobial, antitumor and antihypertensive. Applications of these compounds in the area food technology and pharmaceuticals are also discussed.

Protein Hydrolysates: Uses, Properties and Health Effects goes on to present some biological properties of fish peptides and their beneficial effects on health, emphasizing properties such as antidiabetic neuroprotective and anti-inflammatory, as a natural alternative to drugs and possible strategies to delay cognitive impairment.

As confectionery manufacturers are trying to be innovative in producing suitable fat fillings for various applications. As such, the authors examine the functional, rheological and sensory properties of confectionery fat filling supplemented with different concentrations of bioactive whey protein hydrolysate powders, produced by enzymatic and microbial modification of whey proteins.

Next, the bioactive potential of hydrolysate powders produced by enzymatic and microbial hydrolysis of whey proteins followed by spray drying is examined in order to determine which process allows for a highly bioactive production.

A strain-substrate combination is introduced which allows for the production of dairy protein hydrolysates with high antioxidant activity and improved functional properties, which may be used as high-quality food supplements.

The traditional methods for the production of functional peptides from biological sources are time-consuming and tedious. In the drug industry, it takes about five to ten years from the discovery of an industrial bioactive peptide to market delivery. To overcome the drawbacks of these traditional methods, the authors propose that a fast and versatile method is necessary.

The concluding chapter presents an overview of the production and applications of bioactive peptides, demonstrating their potential use as helper agents of health processes. These peptides may aid in traditional health treatments since they can be used in high concentrations without associated toxic effects.

Binding: Softcover
Binding: e-Book

ISBN: 978-1-53614-898-5
ISBN: 978-1-53614-888-6

Price: $95.00
Price: $95.00


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Carboxymethyl Cellulose. Volume II: Pharmaceutical and Industrial Applications

Editor: Md. Ibrahim H. Mondal
(Polymer and Textiles Research Lab, Department of Applied Chemistry and Chemical Engineering, Rajshahi University, Rajshahi, Bangladesh)

Series: Biochemistry Research Trends

Publication Date: 2019

Book Description:
Carboxymethylcellulose (CMC), also known as cellulose gum, is manufactured by the chemical synthesis of naturally-derived cellulose with chloroacetic acid. The multifunctional aspects of this product make it favorable for use as a key intermediate or ingredient in several applications. Furthermore, CMC is incorporated as a binding, thickening, stabilizing, emulsifying, suspending, sizing and coating agent in various applications. Cellulose gum enhances the aesthetics of the finished product by imparting a smooth texture and modifies the viscosity of various foods and beverages, superabsorbent hydrogels (as in many personal care products), cosmetics and pharmaceuticals. Textiles, paper and board, oil and gas drilling, paints and adhesives, and soaps and detergents are other major applications in the global market. The present book thus covers a wide range of applications; hence, a great number of people, both academics and industrialists, may find topics of interest about CMC, as well as other cellulosics.

Although there are many research publications, patents and reports on CMC, no books about it are yet available. The present book reviews some vital issues and topics on the latest scientific and technological advances in carboxymethylcellulose. This book will provide an essential source of information to readers, in the exploration of possible applications of CMC, and in the generation of new ideas for product development.

The book is divided into two volumes: Carboxymethyl Cellulose: Volume I – Synthesis and Characterization, and Carboxymethyl Cellulose: Volume II – Pharmaceutical and Industrial Applications. The book contains a total of 32 entries on selected topics. Each chapter describes some specific issues and gives the current status of research and technology in the study of synthesis routes or design concepts, methods and fabrication strategies, characterization and applications of CMC products, as well as future prospects for research in the subject area.

Highlights of this book include synthesis and formation mechanisms of CMC, structure property relationships, homogeneous and heterogeneous phase modification to create common and functional products, analysis and characterization, absorption and swelling mechanisms, stimuli-responsive and super-absorbency nature, and a wide range of multi-dimensional applications, including human consumption and uses.

Binding: Hardcover
Binding: e-Book

ISBN: 978-1-53614-751-3
ISBN: 978-1-53614-752-0

Price: $230.00
Price: $230.00


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Caenorhabditis elegans – An Overview and Emerging Roles in Studying Disease

Editor: Daiana S. Avila (Federal University of Pampa, Bagé – RS, Brazil)

Series: New Developments in Medical Research

Publication Date: 2019

Book Description:
Caenorhabditis elegans – An Overview and Emerging Roles in Studying Disease explores different disease models that have been successfully validated in this nematode, either to unravel disease mechanisms or to perform drug screenings. This nonpathogenic organism has helped to firstly identify genetic mechanisms important in cancer (Ras and Bcl oncogene signaling), aging (insulin signaling), and nervous system development (UNC-6/Netrin signaling). Human conditions such as aging/frailty (Chapter One), metabolic syndrome (Chapter Two), neurodegenerative diseases (Chapters Three and Four) and neurodegeneration induced by chemicals (Chapters Three and Five) are recapitulated in C. elegans. The construction of transgenic animals that mimic the diseases, the advances in understanding molecularly these conditions, potential new treatments and limitations of the models are reviewed in these chapters. Notably, the authors that contributed to this book are from different parts of the world due to the widespread use of this nematode in research.

Binding: Hardcover
Binding: e-Book

ISBN: 978-1-53614-946-3
ISBN: 978-1-53614-947-0

Price: $195.00
Price: $195.00


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Parasitoids: Biology, Behavior and Ecology

Editor: Emily Donnelly

Series: Parasites and Parasitic Diseases

Publication Date: 2019

Book Description:
Most insect parasitoids are related to two insect orders, Diptera and Hymenoptera, some having a specific host while others have a vast host range. As such, the opening chapter of Parasitoids: Biology, Behavior and Ecology discusses the influence of host preference and host specificity in biological control programs and their role in different biological control methods.

The behavioral responses of parasitoids can determine the efficiency of a parasitoid species to control host pests. The functional response is one of the most important behavioral responses. The authors show that type II functional response is more common than the other types (I, III, IV and V) of functional response for most parasitoid species. In some research, type III functional response was also reported for parasitoids.

The closing study hypothesized that conditioned parasitoids will parasitize more target hosts compared with individuals without prior conditioning. In conditioning experiments, females of the wasp Trichogramma cacoeciae, a generalist egg parasitoid, oviposited in Lobesia botrana eggs while exposed to L. botrana’s synthetic sex pheromone. Contrary to the hypothesis, this treatment failed to increase the parasitism rate in a subsequent exposure to the conditioned olfactory cue.

Binding: Softcover
Binding: e-Book

ISBN: 978-1-53615-197-8
ISBN: 978-1-53615-198-5

Price: $82.00
Price: $82.00


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Peroxisome Proliferator-Activated Receptors (PPARs): Structure, Mechanisms of Action and Role in Health and Disease

Editor: Rodrigo B. Valenzuela (Nutrition Department, Faculty of Medicine, University of Chile, Casilla, Santiago, Chile)

Series: Biochemistry Research Trends

Publication Date: 2019

Book Description:
Worldwide, the prevalence of chronic diseases, such as obesity, diabetes, cardiovascular diseases, cancer, non-alcoholic fatty liver disease, inflammatory (autoimmune) and neurodegenerative diseases, has shown a sharp increase. In the last 20 years, developing countries and the young population have presented the largest augment in the incidence of these diseases, which evidences that they are not only limited to developed countries nor the adult population. These pathologies have in common a complex interaction between genetic, metabolic and environmental factors.

In this context, several basic and clinical researches have demonstrated the relevance of the expression and activity of the peroxisomal proliferator-activated receptors (PPARs) as fundamental elements in the prevention and treatment of chronic diseases. PPARs are a family of transcription factors that control many cellular metabolic processes. PPAR isoform expression and activity is regulated in different tissues according to physiological processes (growth, development, and aging) and to pathological conditions (cardiovascular diseases, inflammatory diseases, neurodegenerative diseases, hepatic diseases, among others). Also, different compounds such as drugs (fibrates), nutrients (long-chain polyunsaturated fatty acids), and several natural bioactive compounds (polyphenols) are molecular regulators of PPARs expression and activity. Recent research has established the importance of the regulation of PPARs activity and their role in cell and tissue protection against injury (i.e., oxidative stress, inflammation, endoplasmic reticulum stress).

This book is dedicated to reviewing the state of the art regarding PPARs regulation with an emphasis on molecular aspects underlying their effect in health and disease. Specifically, the participation of PPARs is discussed in insulin resistance, inflammation, NAFLD, DM2, cardiovascular disease, hypertension, obesity, gastrointestinal disease, and neurological health and disease. Moreover, this book reviews how different molecules regulate the expression and activity of PPARs. Finally, the scientific information presented in this book pretends to contribute to a greater understanding of PPAR role in the prevention and treatment of different pathologies and metabolic alterations.

Binding: Hardcover
Binding: e-Book

ISBN: 978-1-53614-737-7
ISBN: 978-1-53614-738-4

Price: $230.00
Price: $230.00


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Aflatoxins and Wildlife: Exposure, Problems, Detection and Control Methods

Editors: Scott E. Henke, Ph.D. and Alan Fedynich
Texas A&M University, Kingsville, TX

Series: Animal Science, Issues and Research

Publication Date: 2019

Book Description:
Aflatoxins are a highly toxic group of secondary metabolites that are produced by soil fungi, especially Aspergillus spp. fungi. The fungi infect cereal grain crops including corn, wheat, cotton, peanuts, and various other nuts. Aflatoxins can cause serious health concerns because they are known carcinogens, mutagens, teratogens, and immunosuppressive agents. Therefore, limits are in place by the U.S. Food and Drug Administration regarding how much aflatoxin can occur in cereal grain that will be consumed by humans and livestock within the human food chain. Such limits are even stricter in Europe than in the United States. Therefore, aflatoxins, when present in cereal grains, contribute to major economic losses in these commodities. However, to date in the United States, aflatoxin concentrations are not restricted within cereal grain provided to wildlife. Various wildlife agencies and organizations recommend limits in aflatoxin concentrations, but these are only recommendations and not mandated by law. Therefore, grain condemned for human consumption can be marketed as feed for wildlife. Unfortunately, wild animals befall the same health concerns as humans when it comes to aflatoxin exposure.

Aflatoxins in Wildlife is a compilation of research concerning the effects of aflatoxin exposure to wildlife by researchers of the Caesar Kleberg Wildlife Research Institute at Texas A&M University-Kingsville. This volume contains sixteen chapters, beginning with a review of aflatoxin, what it is, how it functions in the environment, and its known effects on various species (Chapter One and Two). The book then discusses the potential exposure of wildlife to aflatoxins (Chapter Three), and the prevalence of aflatoxins in feed provided to wildlife (Chapters Four–Six). Chapters Seven–Ten focus on specific effects that aflatoxins have on the physiology of wildlife species, mainly birds, while Chapters Eleven and Twelve research the recovery time needed after aflatoxin exposure and the ability of species to detect aflatoxin within feed. Chapter Thirteen specifically addresses the effects of aflatoxin exposure in wild mammals. The remainder of the book (Chapters Fourteen–Sixteen) focus on testing feed for aflatoxin and how a person can reduce the risk of providing aflatoxin-contaminated grain to wildlife. Aflatoxins in Wildlife is an essential addition to the library of vertebrate and environmental toxicologists, zoonotic disease specialists, veterinary health care professionals, and wildlife biologists.

Scott E. Henke is a wildlife research scientist with the Caesar Kleberg Wildlife Research Institute and a Regents Professor and Chair within the Department of Animal, Rangeland and Wildlife Sciences with Texas A&M University-Kingsville. Dr. Henke has >150 publications in scientific journals and also is co-Editor of the books Becoming a Wildlife Professional and American Alligators: Habitats, Behaviors, and Threats. Alan M. Fedynich is a wildlife research scientist with the Caesar Kleberg Wildlife Research Institute and a Professor within the Department of Animal, Rangeland and Wildlife Sciences with Texas A&M University-Kingsville. Dr. Fedynich has authored/coauthored >70 articles published in peer-reviewed scientific journals. The two researchers have collaborated on numerous zoonotic disease and parasite projects.

Binding: Hardcover
Binding: e-Book

ISBN: 978-1-53614-578-6
ISBN: 978-1-53614-579-3

Price: $195.00
Price: $195.00


Cover

Lignin: Biosynthesis, Functions and Economic Significance

Editors: Fachuang Lu, Ph.D.
(Biochemistry Department and Great Lakes Bioenergy Research Center, University of Wisconsin-Madison, Wisconsin Energy Institute, Wisconsin, US
State Key Laboratory of Pulping and Paper Engineering, School of Light Industry Science and Engineering, South China University of Technology, Guangzhou, China)
Fengxia Yue, Ph.D.
(South China University of Technology, Guangzhou, China)

Series: Biochemistry Research Trends

Publication Date: 2019

Book Description:
Lignin is the main natural resource of aromatic structures on Earth. With the depletion of fossil oil and increased environmental concerns, renewable resources for energy and chemical production have attracted tremendous attention from scientists and engineers. As a renewable aromatic polymer, lignin has been, for a long time, studied in terms of its biosynthesis, structures, reactivities and applications although few portions of lignins available from the industry, mainly pulping mills, have been utilized for various applications. The key for complete and efficient utilization of lignins is that all aspects, including lignin biosynthesis, structures, functionalities, and properties, about lignins should be understood. Another important attribute related to lignin utilization comes from analytical methods essential for our understanding of lignins and mechanisms involved in various processes. This book provides critical reviews and the latest research results relating to selected fields of lignin biosynthesis, functional characterization and applications.

Binding: Hardcover
Binding: e-Book

ISBN: 978-1-53614-769-8
ISBN: 978-1-53614-770-4

Price: $230.00
Price: $230.00